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KMID : 0380620210530030239
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Korean Journal of Food Science and Technology
2021 Volume.53 No. 3 p.239 ~ p.244
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Residue analysis and risk assessment of ethoxyquin and ethoxyquin dimer in farmed fish
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Choi Young-Hee
Ko Suk-Kyung
Ryu Seung-Hee
Jin Young-Hee
Kwak Jae-Eun
Lee Myung-Sook
Kim Bog-Soon
Hang In-Sook
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Abstract
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In the present study, liquid chromatography tandem-mass spectrometry was used to conduct a risk assessment of ethoxyquin and ethoxyquin dimer residues in 288 farmed fish sold in wholesale and traditional markets in Seoul. The detection range (detection rate) of ethoxyquin and ethoxyquin dimer was 0.005~0.309 mg/kg (4.9%) and 0.001~2.828 mg/ kg (69.8%), respectively. Ethoxyquin was detected only in freshwater eels, loaches, catfish, and flatfish, whereas ethoxyquin dimer was present in all fish species. To estimate the dietary exposure levels of ethoxyquin and ethoxyquin dimer, the hazard index, calculated using the acceptable daily intake and estimated daily intake, ranged from 0.001 to 0.300%. Our results indicate that there is no significant exposure risk to humans from these farmed fish despite 10 farmed fish samples exceeding the maximum residue level (1.0 mg/kg as the sum of ethoxyquin and ethoxyquin dimer).
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KEYWORD
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ethoxyquin, ethoxyquin dimer, risk assessment, LC-MS/MS, hazard index
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